Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29392855 | 1.00 | KAT2B (0.59) | KAT2BMAPTLMNASMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL141377 | 0.99 | KAT2B (0.61) | KAT2BMAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL2472513 | 0.89 | KAT2B (0.60) | KAT2BMAPTLMNASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10781769 | 0.87 | KAT2B (0.61) | KAT2BMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20420165 | 0.87 | MAPT (0.58) | KAT2BMAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL10580319 | 0.86 | MAPT (0.58) | KAT2BMAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL762553 | 0.86 | SMN1; SMN2 (0.60) | KAT2BMAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL10576590 | 0.86 | LMNA (0.68) | KAT2BMAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL739095 | 0.84 | MAPT (0.64) | KAT2BMAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL16211097 | 0.84 | MAPT (0.57) | KAT2BMAPTLMNASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 934 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1437123-B2 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'ORÉAL (FR) | 2017-11-08 | — | — | EP | claimed |
| EP-0999823-B2 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2011-10-05 | — | — | EP | claimed |
| EP-1666095-B1 | Composition for simultaneous colouring and decolouring of keratinic fibers comprising a meta substituted o-nitroaniline | OREAL (FR) | 2010-05-19 | — | — | EP | claimed |
| EP-2158942-A2 | Direct hair dye composition comprising insoluble oxygenated compounds and processes | L'Oreal (FR) | 2010-03-03 | — | — | EP | claimed |
| US-7651534-B2 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | L'OREAL SA (FR) | 2010-01-26 | — | — | US | claimed |
| EP-1757326-B1 | Direct dying composition comprising insoluble oxygenated compounds and processes | OREAL (FR) | 2009-01-07 | — | — | EP | claimed |
| US-7452386-B2 | Composition for bleaching and simultaneously dyeing keratin fibers, comprising meta-substituted ortho-nitroaniline | L'OREAL S.A. (FR) | 2008-11-18 | — | — | US | claimed |
| EP-1437123-B1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2007-06-06 | — | — | EP | claimed |
| US-20070044251-A1 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | L'OREAL S.A. (FR) | 2007-03-01 | — | — | US | claimed |
| EP-1757326-A1 | Direct dying composition comprising insoluble oxygenated compounds and processes | L'Oréal (FR) | 2007-02-28 | — | — | EP | claimed |
| EP-0673926-B1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | OREAL (FR) | 1997-04-09 | — | — | EP | claimed |
| US-5516942-A | DIRECT DYES FOR HAIR FOR YELLOW OR PURPLE | L'OREAL (FR) | 1996-05-14 | — | — | US | claimed |
| EP-0673926-A1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | L'OREAL (FR) | 1995-09-27 | — | — | EP | claimed |
| EP-0646108-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1995-04-05 | — | — | EP | claimed |
| EP-0646109-A1 | NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES. | OREAL (FR) | 1995-04-05 | — | — | EP | claimed |
| EP-0480829-B1 | Hair dyeing composition containing anthraquinones | OREAL (FR) | 1994-04-06 | — | — | EP | claimed |
| WO-1994000414-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1994-01-06 | — | — | WO | claimed |
| WO-1994000415-A1 | NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1994-01-06 | — | — | WO | claimed |
| US-5226924-A | 1,4-DI(MONO- OR POLY) HYDROXYALKYLAMINO-9,10-ANTHRAQUINONES FOR DYEING HUMAN KERATINOUS FIBRES, COSMETIC COMPOSITION CONTAINING THEM IN COMBINATION WITH AZO AND NITROBENZENE DYES, AND HAIR-DYEING PROCESS USING THEM | L'OREAL (FR) | 1993-07-13 | — | — | US | claimed |
| EP-0480829-A1 | Hair dyeing composition containing anthraquinones | L'OREAL (FR) | 1992-04-15 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070044251-A1 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | KRT18, DSG1, PLOD2 | KAT2B 484/4885MAPT 645/4885LMNA 1708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.