Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979295 | 0.75 | SIGMAR1 (1.00) | SIGMAR1POLBHSD17B10CHRM5CHRM1 | |
| SCHEMBL976125 | 0.75 | SIGMAR1 (1.00) | SIGMAR1POLBHSD17B10CHRM5CHRM1 | |
| SCHEMBL19652101 | 0.74 | SIGMAR1 (0.55) | SIGMAR1POLBHSD17B10KDM4EMEN1 | |
| SCHEMBL13461316 | 0.73 | POLB (0.44) | SIGMAR1POLBKDM4EMEN1KMT2A | |
| SCHEMBL975896 | 0.72 | SIGMAR1 (0.73) | SIGMAR1POLBHSD17B10CHRM5CHRM1 | |
| SCHEMBL11556798 | 0.72 | SIGMAR1 (0.53) | SIGMAR1POLBHSD17B10KDM4EEPHX2 | |
| SCHEMBL10308298 | 0.72 | EPHX1 (0.59) | SIGMAR1KDM4EEPHX2ALDH1A1 | |
| SCHEMBL19696814 | 0.72 | EPHX1 (0.59) | SIGMAR1KDM4EEPHX2ALDH1A1 | |
| SCHEMBL3268411 | 0.71 | PIK3CD (0.46) | SIGMAR1POLBHSD17B10CHRM5CHRM1 | |
| SCHEMBL21164490 | 0.71 | POLB (0.45) | SIGMAR1POLBMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | claimed |
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |