Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 7/20 | 0.63 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9762241 | 0.99 | HTR3A (0.62) | HTR3ASOS1PIM1HTR6DPP4 | |
| SCHEMBL9762192 | 0.82 | KDM4E (0.49) | HTR3A | |
| SCHEMBL9761998 | 0.81 | KDM4E (0.53) | HTR3A | |
| Hydrochloric Acid SCHEMBL9761957 | 0.81 | KDM4E (0.48) | HTR3A | |
| SCHEMBL9023706 | 0.81 | HTR3A (0.85) | HTR3ASOS1 | |
| SCHEMBL12354287 | 0.79 | HTR3A (0.50) | HTR3ASOS1PIM1 | |
| Lerisetron SCHEMBL141124 | 0.78 | HTR3A (1.00) | HTR3ASOS1 | |
| Lerisetron SCHEMBL30669539 | 0.78 | HTR3A (1.00) | HTR3ASOS1 | |
| Lerisetron SCHEMBL29040939 | 0.77 | HTR3A (0.97) | HTR3ASOS1 | |
| SCHEMBL8352617 | 0.76 | HTR3A (0.58) | HTR3ASOS1PIM1HTR6DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023256-A | Antihistamines | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-06-11 | — | — | US | disclosed |