Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418021 | 0.81 | ALDH1A1 (0.46) | TSHR | |
| SCHEMBL9418015 | 0.81 | ALDH1A1 (0.46) | TSHR | |
| SCHEMBL4605693 | 0.81 | ALDH1A1 (0.46) | TSHR | |
| SCHEMBL9598549 | 0.80 | LTA4H (0.47) | LMNATSHRHTTKCNH2HIF1A | |
| SCHEMBL8051743 | 0.80 | S1PR3 (0.40) | LMNACYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL7892665 | 0.77 | ALDH1A1 (0.48) | LMNATSHRHTT | |
| SCHEMBL10717209 | 0.75 | TSHR (0.67) | LMNATSHR | |
| SCHEMBL25168492 | 0.75 | ALDH1A1 (0.54) | LMNATSHR | |
| SCHEMBL11020020 | 0.75 | KCNH2 (0.44) | LMNACYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL28874158 | 0.74 | MCHR1 (0.53) | LMNACYP2D6CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3209341-A | — | — | None | — | — | JP | disclosed |
| JP-H03209341-A | METHOD FOR MAKING OCTYLOXY SUBSTITUTED DIPHENYL IODONIUM HEXAFLUORO METALLOID SALT | GENERAL ELECTRIC CO <GE> | 1991-09-12 | — | — | JP | disclosed |