Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757426 | 0.94 | PDE10A (0.45) | ALOX5CYSLTR1PDE10A | |
| SCHEMBL9757459 | 0.85 | ALOX5 (0.47) | ALOX5CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9757031 | 0.83 | CYSLTR1 (0.58) | ALOX5CYSLTR1GPBAR1PDE10ACYSLTR2 | |
| SCHEMBL9757076 | 0.83 | ALOX5 (0.59) | ALOX5CYSLTR1GPBAR1PDE10ACYSLTR2 | |
| SCHEMBL9757124 | 0.83 | ALOX5 (0.58) | ALOX5CYSLTR1GPBAR1PDE10ACYSLTR2 | |
| SCHEMBL9756987 | 0.81 | PDE10A (0.49) | ALOX5CYSLTR1GPBAR1PDE10ACYSLTR2 | |
| SCHEMBL9766867 | 0.79 | CYSLTR1 (0.45) | CYSLTR1PDE10A | |
| SCHEMBL9757233 | 0.77 | CYSLTR1 (0.55) | ALOX5CYSLTR1GPBAR1PDE10A | |
| SCHEMBL9757054 | 0.77 | PDE10A (0.58) | ALOX5CYSLTR1GPBAR1PDE10ACYSLTR2 | |
| SCHEMBL9757119 | 0.76 | PDE10A (0.54) | ALOX5CYSLTR1GPBAR1PDE10ACYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041453-A | Quinolinyl-benzoheterobicyclic derivatives as antagonists of leukotriene D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-08-20 | — | — | US | claimed |
| US-5041453-A | Quinolinyl-benzoheterobicyclic derivatives as antagonists of leukotriene D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-08-20 | — | — | US | disclosed |