Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LY96 | Q9Y6Y9 | 2/20 | 0.36 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.35 |
| ▸ | ABAT | P80404 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Hydroxybenzaldehyde SCHEMBL6942477 | 0.81 | ALDH5A1 (0.50) | KDM4EPTGS2RAB9AMEN1KMT2A | |
| 3-Hydroxybenzaldehyde SCHEMBL9842145 | 0.80 | CCNB2 (0.42) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL190410 | 0.77 | KDM4E (0.64) | KDM4EPTGS2RAB9AEP300MEN1 | |
| SCHEMBL29713168 | 0.77 | KDM4E (0.64) | KDM4EPTGS2RAB9AEP300MEN1 | |
| Salicyladehyde SCHEMBL6290054 | 0.76 | TRIM24 (0.56) | MEN1KMT2ATRIM24TDP1TRIM33 | |
| SCHEMBL27694314 | 0.70 | JAK2 (0.42) | — | |
| Propene SCHEMBL27830749 | 0.69 | JAK2 (0.36) | — | |
| SCHEMBL5136658 | 0.68 | ALDH1A1 (0.43) | KDM4ERAB9AMEN1KMT2AALDH1A1 | |
| 3-Hydroxybenzaldehyde SCHEMBL6269860 | 0.67 | CCNB2 (0.44) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7235002 | 0.65 | CYP2A6 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001123-A | 2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists | MERCK & CO., INC. (US) | 1991-03-19 | — | — | US | disclosed |