Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.50 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 3/20 | 0.34 |
| ▸ | JAK1 | P23458 | 3/20 | 0.34 |
| ▸ | TYK2 | P29597 | 3/20 | 0.34 |
| ▸ | JAK3 | P52333 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Hydroxybenzaldehyde SCHEMBL9842145 | 0.86 | CCNB2 (0.42) | KMT2AMAOBMEN1KDM4EALDH1A1 | |
| SCHEMBL9761005 | 0.81 | KDM4E (0.40) | ALDH5A1ABATKMT2ATDP1MEN1 | |
| Anisaldehyde SCHEMBL6586624 | 0.81 | ALDH1A1 (0.54) | KMT2ATDP1MAOBMEN1RAB9A | |
| Salicyladehyde SCHEMBL6290054 | 0.78 | TRIM24 (0.56) | KMT2ATDP1MEN1JAK2JAK1 | |
| 4-Hydroxybenzaldehyde SCHEMBL10429027 | 0.76 | ALDH1A1 (0.44) | ALDH5A1ABATKMT2AESR1ESR2 | |
| SCHEMBL27694314 | 0.75 | JAK2 (0.42) | JAK2JAK1TYK2JAK3 | |
| Propene SCHEMBL27830749 | 0.74 | JAK2 (0.36) | JAK2JAK1TYK2JAK3 | |
| 4-Hydroxybenzaldehyde SCHEMBL7168177 | 0.73 | ALDH5A1 (0.76) | ALDH5A1ABATKMT2AESR1ESR2 | |
| 4-Hydroxybenzaldehyde SCHEMBL27689568 | 0.72 | ALDH5A1 (0.67) | ALDH5A1ABATKMT2AESR1ESR2 | |
| 3-Hydroxybenzaldehyde SCHEMBL6269860 | 0.72 | CCNB2 (0.44) | KMT2AMAOBMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103539642-A | Method for preparing 3,4,5-trimethoxy-3'-hydroxy-4'-alkoxy diphenylethane | SHANGHAI INST TECHNOLOGY | 2014-01-29 | — | — | CN | claimed |
| EP-4458916-A1 | PHOTOCATALYTICALLY ACTIVE COATING COMPOSITION, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF | TriOptoTec GmbH (DE) | 2024-11-06 | — | — | EP | disclosed |
| CN-110294732-A | Medical compounds and its application for treating hepatopathy | 江苏新元素医药科技有限公司 | 2019-10-01 | — | — | CN | disclosed |
| CN-103539642-A | Method for preparing 3,4,5-trimethoxy-3'-hydroxy-4'-alkoxy diphenylethane | SHANGHAI INST TECHNOLOGY | 2014-01-29 | — | — | CN | disclosed |
| CN-101829098-B | Application of substituted isosilybin in preparing medicament for treating virus hepatitis B | UNIV DALI | 2012-10-17 | — | — | CN | disclosed |
| CN-1898240-B | Imidazopyrazine tyrosine kinase inhibitors | OSI PHARM INC | 2011-08-03 | — | — | CN | disclosed |
| CN-101829098-A | Application of substituted isosilybin in preparing medicament for treating virus hepatitis B | UNIV DALI | 2010-09-15 | — | — | CN | disclosed |
| CN-1898240-A | Imidazopyrazine tyrosine kinase inhibitors | OSI PHARM INC (US) | 2007-01-17 | — | — | CN | disclosed |
| EP-1121338-A4 | METHOD FOR SYNTHESIZING DIARYL-SUBSTITUTED HETEROCYCLIC COMPOUNDS, INCLUDING TETRAHYDROFURANS | MILLENNIUM PHARM INC (US) | 2003-03-12 | — | — | EP | disclosed |
| US-20020128491-A1 | Method for synthesizing diaryl-substituted heterocyclic compounds, including tetrahydrofurans | RAO ALLA VENKATA RAMA (IN) | 2002-09-12 | — | — | US | disclosed |
| US-6403814-B1 | REACTING WITH GRIGNARD REAGENT COMPOUND HAVING CARBON SUBSTITUTED BY ACETYLENE GROUP, ARYL GROUP AND HYDROXYL GROUP, HYDROGENATING ACETYLENE MOIETY OF REACTION PRODUCT, CYCLIZING TO PROVIDE DI-ARYL TETRAHYDROFURAN | MILLENNIUM PHARMACEUTICALS, INC. | 2002-06-11 | — | — | US | disclosed |
| EP-1121338-A1 | METHOD FOR SYNTHESIZING DIARYL-SUBSTITUTED HETEROCYCLIC COMPOUNDS, INCLUDING TETRAHYDROFURANS | Millennium Pharmaceuticals, Inc. (US) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000023409-A1 | METHOD FOR SYNTHESIZING DIARYL-SUBSTITUTED HETEROCYCLIC COMPOUNDS, INCLUDING TETRAHYDROFURANS | LEUKOSITE, INC. (US) | 2000-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128491-A1 | Method for synthesizing diaryl-substituted heterocyclic compounds, including tetrahydrofurans | TPMT, TPI1, GTF2I | ALDH5A1 883/4885ABAT 1343/4885KMT2A 1424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.