Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 5/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761046 | 0.84 | ALDH1A1 (0.51) | TSHRKDM4E | |
| SCHEMBL9760156 | 0.81 | KDM4E (0.46) | TSHRKDM4EPOLB | |
| SCHEMBL8351725 | 0.81 | TSHR (0.64) | TSHRKDM4EPOLB | |
| SCHEMBL9761030 | 0.80 | HTR6 (0.46) | TSHRHTR6KDM4E | |
| SCHEMBL8358959 | 0.74 | TSHR (0.52) | TSHRKDM4E | |
| SCHEMBL9789247 | 0.72 | TSHR (0.43) | TSHRP2RX7KDM4ECCR4 | |
| SCHEMBL10658767 | 0.72 | TSHR (0.47) | TSHRPOLB | |
| SCHEMBL10668742 | 0.70 | TSHR (0.42) | TSHRCCR4 | |
| SCHEMBL10774163 | 0.69 | KDM4E (0.44) | TSHRHTR6KDM4E | |
| SCHEMBL8357182 | 0.69 | TSHR (0.43) | TSHRCCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992091-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-02-12 | — | — | US | claimed |
| US-5021591-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-06-04 | — | — | US | disclosed |
| US-4997940-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-03-05 | — | — | US | disclosed |
| US-4992091-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-02-12 | — | — | US | disclosed |