Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761206 | 0.84 | TSHR (0.44) | KDM4ETSHR | |
| SCHEMBL9760377 | 0.83 | KDM4E (0.53) | ALDH1A1KDM4EHSD17B10HPGDTP53 | |
| SCHEMBL9792974 | 0.81 | KDM4E (0.53) | ALDH1A1KDM4EHSD17B10HPGDTP53 | |
| SCHEMBL9760156 | 0.76 | KDM4E (0.46) | ALDH1A1KDM4EHSD17B10HPGDTP53 | |
| SCHEMBL8351725 | 0.76 | TSHR (0.64) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL10774291 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDTP53 | |
| SCHEMBL10774163 | 0.74 | KDM4E (0.44) | ALDH1A1KDM4EHSD17B10HPGDTP53 | |
| SCHEMBL9760348 | 0.73 | KDM4E (0.53) | ALDH1A1KDM4EHSD17B10HPGDTP53 | |
| SCHEMBL9831981 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10HPGDTP53 | |
| SCHEMBL10774609 | 0.70 | HTT (0.43) | ALDH1A1KDM4EHPGDTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021591-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-06-04 | — | — | US | disclosed |
| US-4997940-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-03-05 | — | — | US | disclosed |
| US-4992091-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-02-12 | — | — | US | disclosed |