Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6638188 | 0.76 | GALR3 (0.33) | MAPT | |
| SCHEMBL28286529 | 0.74 | MAPT (0.37) | ALDH1A1GAAMAPT | |
| SCHEMBL31327250 | 0.62 | ADORA2A (0.54) | — | |
| SCHEMBL11388739 | 0.61 | L3MBTL1 (0.60) | L3MBTL1TDP1ALDH1A1GAAMAPT | |
| SCHEMBL7701711 | 0.61 | ALDH1A1 (0.35) | ALOX15TDP1ALDH1A1MAPT | |
| SCHEMBL20553556 | 0.61 | ALDH1A1 (0.35) | ALOX15TDP1ALDH1A1MAPT | |
| SCHEMBL29484712 | 0.60 | MGMT (0.43) | TDP1ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL1172667 | 0.59 | — | — | |
| SCHEMBL4213317 | 0.59 | MMP13 (0.33) | ALOX15MAPK1TDP1ALDH1A1MAPT | |
| SCHEMBL21240594 | 0.59 | GALR3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |