SCHEMBL9761442

SCHEMBL9761442

Cc1ccc(S(=O)(=O)N(N)c2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.66
CA9 Q16790 2/20 0.66
C5AR1 P21730 1/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 1/20 0.52
MCOLN3 Q8TDD5 1/20 0.52
CNR2 P34972 4/20 0.48
CNR1 P21554 2/20 0.48
KMT2A Q03164 1/20 0.48
NPSR1 Q6W5P4 2/20 0.47
HTT P42858 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PKM P14618 1/20 0.47
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
PTPRC P08575 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA3 P07451 1/20 0.45
CA6 P23280 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27336572 0.93 CA12 (0.56) CA12CA9C5AR1ALDH1A1MAPT
SCHEMBL7946990 0.90 MAPT (0.62) CA12CA9C5AR1MAPTMCOLN3
SCHEMBL22257152 0.86 APOBEC3G (0.52) CA12CA9ALDH1A1KMT2APKM
SCHEMBL6432835 0.86 APOBEC3G (0.52) CA12CA9ALDH1A1KMT2APKM
SCHEMBL7545347 0.83 PKM (0.48) CA12CA9ALDH1A1MAPTKMT2A
SCHEMBL28374824 0.82 MAPT (0.53) CA12CA9C5AR1ALDH1A1MAPT
SCHEMBL28433742 0.82 KDM4E (0.60) CA12CA9ALDH1A1MAPTMCOLN3
SCHEMBL10956151 0.81 CA12 (0.70) CA12CA9C5AR1ALDH1A1MAPT
SCHEMBL3697451 0.81 PKM (0.71) CA12CA9C5AR1ALDH1A1MAPT
SCHEMBL28429406 0.80 TP53 (0.59) ALDH1A1MAPTMCOLN3CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108276305-B Mild method for preparing Sudan red I structural analogue 江西理工大学 2020-07-31 CN claimed
CN-108276305-A A method of mild prepares Sudan red 1 analogue 江西理工大学 2018-07-13 CN claimed
CN-108276305-B Mild method for preparing Sudan red I structural analogue 江西理工大学 2020-07-31 CN disclosed
CN-108276305-A A method of mild prepares Sudan red 1 analogue 江西理工大学 2018-07-13 CN disclosed
US-5003052-A Monoazo fiber reactive dye for cellulose, polyamides, wool, silk, polyurethanes and leather CIBA-GEIGY CORPORATION (US) 1991-03-26 US disclosed