SCHEMBL3697451

SCHEMBL3697451

Cc1ccc(S(=O)(=O)N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.71
CA12 O43570 1/20 0.70
CA9 Q16790 1/20 0.70
ALDH1A1 P00352 2/20 0.69
ESR1 P03372 1/20 0.67
C5AR1 P21730 1/20 0.56
MAPT P10636 2/20 0.55
MCOLN3 Q8TDD5 1/20 0.55
KDM4E B2RXH2 1/20 0.51
CNR2 P34972 4/20 0.50
NPSR1 Q6W5P4 3/20 0.50
CNR1 P21554 2/20 0.50
KMT2A Q03164 1/20 0.50
HTT P42858 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KEAP1 Q14145 1/20 0.49
NFE2L2 Q16236 1/20 0.49
PTPRC P08575 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28634601 0.94 ALDH1A1 (0.66) PKMCA12CA9ALDH1A1ESR1
SCHEMBL3702995 0.92 ALDH1A1 (0.63) PKMCA12CA9ALDH1A1ESR1
SCHEMBL3886338 0.90 ALDH1A1 (0.62) PKMCA12CA9ALDH1A1ESR1
SCHEMBL3701001 0.90 MAPT (0.67) PKMCA12CA9ALDH1A1ESR1
SCHEMBL6158839 0.87 ALDH1A1 (0.59) PKMCA12CA9ALDH1A1ESR1
SCHEMBL6158969 0.86 ALDH1A1 (0.58) PKMCA12CA9ALDH1A1ESR1
SCHEMBL28380035 0.86 NPSR1 (0.69) PKMCA12CA9ALDH1A1ESR1
SCHEMBL6157398 0.86 ALDH1A1 (0.58) PKMCA12CA9ALDH1A1ESR1
SCHEMBL6158520 0.86 ALDH1A1 (0.61) PKMCA12CA9ALDH1A1ESR1
SCHEMBL812682 0.85 PKM (0.79) PKMCA12CA9ALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113582947-A Method for removing sulfonyl protection of amine 南开大学 2021-11-02 CN disclosed
WO-2020011935-A1 DIBENZOTHIOPENE SALT AS ALKINYLATING AND CYANATING AGENT Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts (DE) 2020-01-16 WO disclosed
CN-102472966-A Negative photosensitive resin composition, polyimide resin film using same, and flexible printed circuit board SUMITOMO ELECTRIC INDUSTRIES 2012-05-23 CN disclosed
US-20120118616-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, POLYIMIDE RESIN FILM USING SAME, AND FLEXIBLE PRINTED CIRCUIT BOARD SUMITOMO ELECTRIC PRINTED CIRCUITS, INC. (JP) 2012-05-17 US disclosed
WO-2005030730-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE α-AMINO-ϵ-CAPROLACTAM OR SALT THEREOF AND INTERMEDIATE FOR THE PRODUCTION YAMAKAWA CHEMICAL INDUSTRY CO., LTD. (JP) 2005-04-07 WO disclosed
EP-1457487-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE CIS-PIPERIDINE DERIVATIVES Toray Fine Chemicals Co., Ltd. (JP) 2004-09-15 EP disclosed
US-20040171836-A1 Method for producing optical-active cis-piperidine derivatives TORAY FINE CHEMICALS CO., LTD., A CORPORATION OF JAPAN, (JP) 2004-09-02 US disclosed
EP-0289780-A2 Thermoplastic moulding compounds on the basis of polyphenylene ether BASF Aktiengesellschaft (DE) 1988-11-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171836-A1 Method for producing optical-active cis-piperidine derivatives TYR, DDC, TARBP1 PKM 1651/4885CA12 4430/4885CA9 1639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.