SCHEMBL6432835

SCHEMBL6432835

NN(c1ccccc1)S(=O)(=O)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APOBEC3G Q9HC16 1/20 0.52
ALDH1A1 P00352 2/20 0.50
PKM P14618 1/20 0.50
ESR1 P03372 2/20 0.47
CA12 O43570 2/20 0.46
CA9 Q16790 2/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
PLA2G7 Q13093 1/20 0.46
CA13 Q8N1Q1 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
KMT2A Q03164 1/20 0.46
HTR6 P50406 1/20 0.44
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22257152 1.00 APOBEC3G (0.52) APOBEC3GALDH1A1PKMESR1CA12
SCHEMBL14940242 0.88 CYP3A4 (0.47) APOBEC3GALDH1A1PKMCA12CA9
SCHEMBL7545347 0.88 PKM (0.48) ALDH1A1PKMESR1CA12CA9
SCHEMBL9761442 0.86 CA12 (0.66) ALDH1A1PKMCA12CA9CA1
SCHEMBL9943359 0.86 PGR (0.49) APOBEC3GALDH1A1PKMCA12CA9
SCHEMBL3978127 0.78 APOBEC3G (0.58) APOBEC3GALDH1A1PKMESR1CA12
SCHEMBL9735258 0.77 KMT2A (0.50) APOBEC3GALDH1A1CA12CA9CA1
SCHEMBL812682 0.76 PKM (0.79) APOBEC3GALDH1A1PKMESR1CA12
SCHEMBL11576079 0.76 APOBEC3G (0.56) APOBEC3GALDH1A1PKMESR1CA12
SCHEMBL633874 0.76 CA2 (0.45) ALDH1A1PKMESR1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111587116-A Decreasing beta-catenin and IDO expression to boost immunotherapy 迪克纳制药公司 2020-08-25 CN claimed
CN-111587116-A Decreasing beta-catenin and IDO expression to boost immunotherapy 迪克纳制药公司 2020-08-25 CN disclosed
CN-108276305-A A method of mild prepares Sudan red 1 analogue 江西理工大学 2018-07-13 CN disclosed
EP-1238010-B1 USE OF A MASTERBATCH TO PRODUCE A CORK TOTAL PETROCHEMICALS RES FELUY (BE) 2005-07-06 EP disclosed
US-6852764-B2 Blend for masterbatches ATOFINA RESEARCH S.A. (BE) 2005-02-08 US disclosed
US-20030050353-A1 Blend for masterbatches TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2003-03-13 US disclosed
EP-1238010-A1 BLEND FOR MASTERBATCHES ATOFINA Research (BE) 2002-09-11 EP disclosed
WO-2001042354-A1 BLEND FOR MASTERBATCHES ATOFINA RESEARCH (BE) 2001-06-14 WO disclosed
EP-1106650-A1 Blend for masterbatches FINA RESEARCH S.A. (BE) 2001-06-13 EP disclosed
US-5760196-A PRINTING AND DYEING HYDROPHOBIC FIBERS OF POLYESTERS FOR COLORFASTNESS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-06-02 US disclosed
EP-0727464-A2 Monoazo compounds and methods for dyeing or printing hydrophobic fiber materials using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-08-21 EP disclosed
EP-0186020-A1 Method for producing handles Beiersdorf Aktiengesellschaft (DE) 1986-07-02 EP disclosed
US-4536441-A STRETCHED AT RIGHT ANGLE TO WEB BEIERSDORF AKTIENGESELLSCHAFT (DE) 1985-08-20 US disclosed
EP-0129809-A1 Foam-sheet and adhesive tape backed with foam-sheet Beiersdorf Aktiengesellschaft (DE) 1985-01-02 EP disclosed