Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762513 | 0.82 | MAPT (0.43) | KMT2AL3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL9761589 | 0.75 | KMT2A (0.44) | KMT2AL3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL9762588 | 0.74 | — | — | |
| SCHEMBL9761231 | 0.72 | ALDH1A1 (0.41) | KMT2AMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL9761801 | 0.67 | KMT2A (0.37) | KMT2AL3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL9762334 | 0.64 | ALDH1A1 (0.41) | KMT2AMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9762166 | 0.64 | MAPT (0.46) | KMT2AL3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL9761185 | 0.62 | L3MBTL1 (0.40) | KMT2AL3MBTL1HTTMAPTSMN1; SMN2 | |
| SCHEMBL18660604 | 0.62 | KMT2A (0.56) | KMT2AHTTMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9761459 | 0.60 | ALDH1A1 (0.39) | KMT2AL3MBTL1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |