Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 8/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761459 | 0.80 | ALDH1A1 (0.39) | KMT2AL3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL9762538 | 0.78 | SMN1; SMN2 (0.38) | MAPTALDH1A1GAARAB9ACYP1A2 | |
| SCHEMBL9761212 | 0.76 | PARP1 (0.36) | KMT2AL3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL9761589 | 0.75 | KMT2A (0.44) | KMT2AL3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL9762348 | 0.75 | — | — | |
| SCHEMBL9761621 | 0.74 | CYP1A2 (0.39) | KMT2AMAPTALDH1A1LMNANPSR1 | |
| SCHEMBL9761748 | 0.74 | HRH1 (0.32) | — | |
| SCHEMBL9761856 | 0.70 | KMT2A (0.40) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL9762513 | 0.69 | MAPT (0.43) | KMT2AL3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL9761506 | 0.67 | KMT2A (0.39) | KMT2AL3MBTL1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |