Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761584 | 0.77 | BRD4 (0.36) | CYP3A4CYP2C9CYP1A2CYP2C19BRD4 | |
| SCHEMBL9760799 | 0.75 | BRD4 (0.37) | BRD4 | |
| SCHEMBL9762330 | 0.74 | CHRM5 (0.43) | CHRM5LMNACYP3A4CHRM4CHRM1 | |
| SCHEMBL9762390 | 0.72 | CHRM5 (0.42) | CHRM5LMNACYP3A4CHRM4CHRM1 | |
| SCHEMBL9762586 | 0.72 | PARG (0.37) | BRD4PARG | |
| SCHEMBL9762213 | 0.72 | BRD4 (0.44) | LMNACYP3A4CYP2C9MEN1CYP2C19 | |
| SCHEMBL9761111 | 0.71 | CYP2C9 (0.38) | CYP2C9CYP2C19BRD4 | |
| SCHEMBL9762493 | 0.69 | BRD4 (0.40) | KDM4EBRD4 | |
| SCHEMBL7613547 | 0.68 | ELANE (0.50) | MEN1KMT2ABRD4 | |
| SCHEMBL2352063 | 0.67 | BRD4 (0.42) | MEN1KMT2AKDM4EMAPTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066665-A | Cognition activators; alzheimer*s disease | WARNER-LAMBERT CO. (US) | 1991-11-19 | — | — | US | claimed |
| US-5066665-A | Cognition activators; alzheimer*s disease | WARNER-LAMBERT CO. (US) | 1991-11-19 | — | — | US | disclosed |