Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PARG | Q86W56 | 3/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760799 | 0.77 | BRD4 (0.37) | BRD4 | |
| SCHEMBL9761609 | 0.77 | CHRM5 (0.41) | BRD4PARGCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9762586 | 0.75 | PARG (0.37) | BRD4PARGXIAP | |
| SCHEMBL9762213 | 0.74 | BRD4 (0.44) | BRD4CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9762539 | 0.72 | CHRM2 (0.36) | PARGARG1SLC6A3XIAPTDP1 | |
| SCHEMBL9762493 | 0.71 | BRD4 (0.40) | BRD4MAP2K1 | |
| SCHEMBL7613547 | 0.70 | ELANE (0.50) | BRD4 | |
| SCHEMBL2352063 | 0.69 | BRD4 (0.42) | BRD4 | |
| SCHEMBL9761743 | 0.69 | BRD4 (0.38) | BRD4PARG | |
| SCHEMBL10460973 | 0.68 | BRD4 (0.39) | BRD4MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066665-A | Cognition activators; alzheimer*s disease | WARNER-LAMBERT CO. (US) | 1991-11-19 | — | — | US | disclosed |