Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762223 | 0.72 | ALDH1A1 (0.46) | KMT2AL3MBTL1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9762560 | 0.69 | PIK3CB (0.49) | KMT2AALDH1A1CYP1A2CYP2C9MAPT | |
| SCHEMBL9761212 | 0.69 | PARP1 (0.36) | KMT2AL3MBTL1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9762532 | 0.67 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL9761085 | 0.67 | MAPT (0.40) | KMT2AL3MBTL1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9762562 | 0.67 | ALDH1A1 (0.38) | KMT2AL3MBTL1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9762325 | 0.66 | ALDH1A1 (0.33) | KMT2AL3MBTL1ALDH1A1MAPTPOLB | |
| SCHEMBL1124092 | 0.66 | ALDH1A1 (0.54) | KMT2AALDH1A1CYP1A2CYP2C9MAPT | |
| SCHEMBL9761124 | 0.64 | KMT2A (0.52) | KMT2AALDH1A1CYP1A2CYP2C9MAPT | |
| SCHEMBL9761268 | 0.62 | CYP1A2 (0.37) | KMT2AALDH1A1CYP1A2CYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |