Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760948 | 0.77 | CYP1A2 (0.36) | KMT2ASMN1; SMN2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL9761212 | 0.77 | PARP1 (0.36) | KMT2ASMN1; SMN2TSHRHSD17B10ALDH1A1 | |
| SCHEMBL9762538 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9MAPT | |
| SCHEMBL9761124 | 0.73 | KMT2A (0.52) | KMT2ASMN1; SMN2TSHRMEN1HSD17B10 | |
| SCHEMBL9761268 | 0.73 | CYP1A2 (0.37) | KMT2ASMN1; SMN2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL9762702 | 0.73 | MAPT (0.33) | ALDH1A1MAPT | |
| SCHEMBL9761801 | 0.70 | KMT2A (0.37) | KMT2ASMN1; SMN2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9762396 | 0.69 | MAPT (0.33) | MAPT | |
| SCHEMBL9761621 | 0.68 | CYP1A2 (0.39) | KMT2ASMN1; SMN2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL9761459 | 0.66 | ALDH1A1 (0.39) | KMT2ASMN1; SMN2MEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |