Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 8/20 | 0.50 |
| ▸ | BRD4 | O60885 | 4/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129169 | 0.87 | BAZ2B (0.45) | BRD4CREBBPTP53PDE4BPDE4D | |
| SCHEMBL9131042 | 0.85 | PTGDR2 (0.46) | BRD4CREBBPTP53PDE4BPDE4D | |
| SCHEMBL9134935 | 0.78 | MAPT (0.43) | TP53PDE4BPDE4DPOLBMAPT | |
| SCHEMBL9727191 | 0.77 | PDE4B (0.41) | TP53PDE4BPDE4DTRPV1NPY5R | |
| SCHEMBL10658791 | 0.74 | PDE4B (0.42) | TP53PDE4BPDE4DTRPV1NPY5R | |
| SCHEMBL9762008 | 0.73 | MAPT (0.45) | BRD4CREBBPTP53POLBMAPT | |
| SCHEMBL10660631 | 0.72 | PDE4B (0.42) | TP53PDE4BPDE4DTRPV1NPY5R | |
| SCHEMBL9726939 | 0.70 | MAPT (0.43) | TP53PDE4BPDE4DPOLBMAPT | |
| SCHEMBL4194695 | 0.69 | PDE4B (0.47) | BRD4TP53PDE4BPDE4DTRPV1 | |
| SCHEMBL10655441 | 0.68 | PDE4B (0.42) | TP53PDE4BPDE4DTRPV1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988705-A | Antiallergens and -inflammatory agents; hypotensive agents immunological suppression; hyperproliferative skin disorders such as psoriasis | SCHERING CORPORATION (US) | 1991-01-29 | — | — | US | claimed |