Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | BAZ2B | Q9UIF8 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129169 | 0.85 | BAZ2B (0.45) | MAPTBAZ2BPOLBLMNABRD4 | |
| SCHEMBL9134935 | 0.76 | MAPT (0.43) | MAPTBAZ2BPOLBLMNATP53 | |
| SCHEMBL9131042 | 0.74 | PTGDR2 (0.46) | MAPTBAZ2BLMNABRD4CREBBP | |
| SCHEMBL9761878 | 0.73 | KCNK3 (0.50) | MAPTPOLBBRD4CREBBPTP53 | |
| SCHEMBL9726939 | 0.68 | MAPT (0.43) | MAPTPOLBTP53KMT2A | |
| SCHEMBL13197666 | 0.66 | P2RX7 (0.65) | KMT2A | |
| SCHEMBL9129122 | 0.65 | CLPP (0.51) | KMT2A | |
| SCHEMBL6009928 | 0.65 | MAPT (0.49) | MAPTKMT2A | |
| SCHEMBL30438257 | 0.65 | MAPT (0.49) | MAPTKMT2A | |
| SCHEMBL7083395 | 0.65 | CREBBP (0.70) | BAZ2BBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988705-A | Antiallergens and -inflammatory agents; hypotensive agents immunological suppression; hyperproliferative skin disorders such as psoriasis | SCHERING CORPORATION (US) | 1991-01-29 | — | — | US | claimed |