Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9390866 | 0.86 | TDP1 (0.55) | TDP1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL331522 | 0.86 | ALDH1A1 (0.64) | TDP1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL6297719 | 0.79 | TDP1 (0.58) | TDP1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL29836953 | 0.77 | ALDH1A1 (0.55) | TDP1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL27710739 | 0.76 | MEN1 (0.53) | TDP1ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL27752710 | 0.76 | ALDH1A1 (0.56) | TDP1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL4649869 | 0.76 | ALDH1A1 (0.53) | TDP1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL31447707 | 0.76 | ALDH1A1 (0.53) | TDP1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL29837196 | 0.76 | ALDH1A1 (0.53) | TDP1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL11012181 | 0.73 | MAPT (0.52) | TDP1TSHRALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297570-B1 | 2,2-BIS-(3-AMINOPHENYL)-HEXAFLUOROPROPANE DERIVATIVES AND PROCESS FOR THE PREPARATION OF 2,2-BIS-(3,4-DIAMINOPHENYL)-HEXAFLUOROPROPANE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-05 | — | — | EP | claimed |
| EP-0297570-A2 | 2,2-Bis-(3-aminophenyl)-hexafluoropropane derivatives and process for the preparation of 2,2-bis-(3,4-diaminophenyl)-hexafluoropropane | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-04 | — | — | EP | claimed |
| EP-0297570-B1 | 2,2-BIS-(3-AMINOPHENYL)-HEXAFLUOROPROPANE DERIVATIVES AND PROCESS FOR THE PREPARATION OF 2,2-BIS-(3,4-DIAMINOPHENYL)-HEXAFLUOROPROPANE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-05 | — | — | EP | disclosed |
| US-4922019-A | Derivatives of 2,2-bis-(3-aminophenyl)hexafluoropropane and process for the preparation of 2,2-bis-(3,4-diaminophenyl)hexafluoropropane | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
| US-4922019-A | Derivatives of 2,2-bis-(3-aminophenyl)hexafluoropropane and process for the preparation of 2,2-bis-(3,4-diaminophenyl)hexafluoropropane | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
| EP-0297570-A2 | 2,2-Bis-(3-aminophenyl)-hexafluoropropane derivatives and process for the preparation of 2,2-bis-(3,4-diaminophenyl)-hexafluoropropane | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-04 | — | — | EP | disclosed |
| EP-0297570-A2 | 2,2-Bis-(3-aminophenyl)-hexafluoropropane derivatives and process for the preparation of 2,2-bis-(3,4-diaminophenyl)-hexafluoropropane | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-04 | — | — | EP | disclosed |