Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.50 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.50 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761896 | 0.86 | TDP1 (0.55) | ALDH1A1TSHRTDP1MAPTLMNA | |
| SCHEMBL30515345 | 0.85 | ALDH1A1 (0.64) | ALDH1A1TSHRTDP1MAPTLMNA | |
| SCHEMBL204956 | 0.85 | ALDH1A1 (0.64) | ALDH1A1TSHRTDP1MAPTLMNA | |
| SCHEMBL11012181 | 0.82 | MAPT (0.52) | ALDH1A1TSHRTDP1MAPTLMNA | |
| SCHEMBL7240751 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MAPTLMNA | |
| SCHEMBL29942185 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MAPTLMNA | |
| SCHEMBL6297719 | 0.81 | TDP1 (0.58) | ALDH1A1TSHRTDP1MAPTLMNA | |
| SCHEMBL3778792 | 0.79 | MAPK1 (0.55) | ALDH1A1TSHRTDP1MAPTLMNA | |
| SCHEMBL113070 | 0.79 | TDP1 (0.60) | ALDH1A1TSHRTDP1MAPTLMNA | |
| SCHEMBL1998640 | 0.79 | CYP3A4 (0.52) | ALDH1A1TSHRTDP1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045195-A | Device for treating carbon tetrachloride through interception net and enzymolysis filler jointly and working method thereof | 徐州市城区水资源管理处 | 2016-10-26 | — | — | CN | claimed |
| CN-102584822-B | 1,3-benzodiazole naphthalimide derivative with C, preparation method and appliance thereof | UNIV SHANGHAI JIAOTONG | 2014-08-06 | — | — | CN | claimed |
| CN-102584822-A | 1,3-benzodiazole naphthalimide derivative with c, preparation method and appliance thereof | UNIV SHANGHAI JIAOTONG | 2012-07-18 | — | — | CN | claimed |
| EP-0568977-B1 | Stabilized aminobenzotrifluorides | HOECHST AG (DE) | 1996-08-21 | — | — | EP | claimed |
| US-5349104-A | Base stabilized compound for heat resistance and storage stability | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-20 | — | — | US | claimed |
| EP-0568977-A2 | Stabilized aminobenzotrifluorides | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-10 | — | — | EP | claimed |
| US-20240376084-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2024-11-14 | — | — | US | disclosed |
| EP-3943087-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2022-01-26 | — | — | EP | disclosed |
| EP-2968337-B1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-07-21 | — | — | EP | disclosed |
| US-10618902-B2 | Substituted pyrido[2,3-d]pyrimidines as inhibitors of protein kinases | CELGENE CAR LLC (BM) | 2020-04-14 | — | — | US | disclosed |
| US-20190218220-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2019-07-18 | — | — | US | disclosed |
| US-10065966-B2 | Substituted pyrido[2,3-d]pyrimidines as inhibitors of protein kinases | CELGENE CAR LLC (BM) | 2018-09-04 | — | — | US | disclosed |
| US-20170267685-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2017-09-21 | — | — | US | disclosed |
| US-4748277-A | FLUORINATION AND HYDROLYSIS OF TRIHALOMETHYLPHENYL ISOCYANATE | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1988-05-31 | — | — | US | disclosed |
| US-4264775-A | BY DIAZOTIZATION OF ANILINES, REACTING WITH A VINYL ESTER, AND REACTING WITH A SECONDARY AMINE | ELI LILLY AND COMPANY (US) | 1981-04-28 | — | — | US | disclosed |
| US-4263441-A | BENZOXAZOLE DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-04-21 | — | — | US | disclosed |
| US-4185018-A | Process for producing benzofurazan-1-oxides | CIBA-GEIGY CORPORATION (US) | 1980-01-22 | — | — | US | disclosed |
| EP-0002030-A1 | Fluorinated benzazole derivatives, method for their preparation and their use as optical brighteners | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-30 | — | — | EP | disclosed |
| US-4107316-A | Fluorurated amides of nicotinic acid and the process for the preparation thereof | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1978-08-15 | — | — | US | disclosed |
| US-3957860-A | SULFAMIC ACID | CIBA-GEIGY AG (CH) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190218220-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | PRKACA, PRKDC, AURKC | ALDH1A1 3719/4885TSHR 4378/4885TDP1 2059/4885 |
| US-20170267685-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | PRKACA, PRKDC, AURKC | ALDH1A1 3719/4885TSHR 4378/4885TDP1 2059/4885 |
| US-10618902-B2 | Substituted pyrido[2,3-d]pyrimidines as inhibitors of protein kinases | PDXK, DCK, DTYMK | ALDH1A1 3786/4885TSHR 3723/4885TDP1 710/4885 |
| US-20240376084-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | SERPINB1, LTA, SERPINC1 | ALDH1A1 3127/4885TSHR 2980/4885TDP1 3869/4885 |
| US-10065966-B2 | Substituted pyrido[2,3-d]pyrimidines as inhibitors of protein kinases | CDK2, PDXK, MAP4K2 | ALDH1A1 3398/4885TSHR 3705/4885TDP1 839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.