Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19834217 | 0.86 | HTT (0.54) | GAAPOLBLMNAALDH1A1HTT | |
| SCHEMBL10797298 | 0.86 | MEN1 (0.44) | GAAPOLBLMNAMAPTHTT | |
| SCHEMBL9762757 | 0.83 | MEN1 (0.50) | POLBLMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10799202 | 0.78 | LMNA (0.40) | GAALMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL5312470 | 0.77 | VDR (0.40) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL9761992 | 0.77 | GAA (0.50) | GAAPOLBLMNAALDH1A1TSHR | |
| SCHEMBL5311911 | 0.76 | VDR (0.39) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL9762899 | 0.74 | GAA (0.48) | GAAPOLBLMNAALDH1A1TSHR | |
| SCHEMBL21131436 | 0.74 | RAPGEF4 (0.47) | GAAPOLBLMNAALDH1A1TSHR | |
| SCHEMBL10797153 | 0.74 | LMNA (0.51) | GAALMNAALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003052-A | Monoazo fiber reactive dye for cellulose, polyamides, wool, silk, polyurethanes and leather | CIBA-GEIGY CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-4652634-A | Water-soluble monoazo compounds containing a N-(sulfoalkyl)-aniline coupling component and a fiber-reactive group of the vinylsulfonyl series in the phenyl or benzothiazole diazo component, suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |
| EP-0051808-B1 | WATER-SOLUBLE MONOAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-04 | — | — | EP | disclosed |