Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4186791 | 0.88 | CYP3A4 (0.59) | ALDH1A1KDM4ECYP3A4CA2RAB9A | |
| SCHEMBL11963923 | 0.85 | POLB (0.53) | GRIN2DGRIN2AGRIN2BGRIN2CKDM4E | |
| SCHEMBL11320167 | 0.84 | CYP3A4 (0.56) | ALDH1A1KDM4ECYP3A4CA2RAB9A | |
| SCHEMBL10989390 | 0.84 | PTPN11 (0.49) | ALDH1A1KDM4ECYP3A4CA2MRGPRX4 | |
| SCHEMBL100476 | 0.83 | ALDH1A1 (0.68) | ALDH1A1CYP3A4RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL487508 | 0.81 | ALDH1A1 (0.61) | ALDH1A1CYP3A4CA2RAB9A | |
| SCHEMBL10996267 | 0.81 | CYP3A4 (0.53) | ALDH1A1KDM4ECYP3A4CA2RAB9A | |
| SCHEMBL14070555 | 0.81 | CYP3A4 (0.53) | ALDH1A1KDM4ECYP3A4CA2RAB9A | |
| SCHEMBL13316465 | 0.81 | GRIN2D (0.53) | GRIN2DGRIN2AGRIN2BGRIN2CKDM4E | |
| SCHEMBL18589717 | 0.80 | GRIN2D (0.46) | GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983756-A | DIAGNOSING LIVER, KIDNEY DISORDERS | NITTO BOSEKI CO., LTD. (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4518609-A | ANTITUMOR, SKIN DISORDERS | SRI INTERNATIONAL (US) | 1985-05-21 | — | — | US | disclosed |
| US-4456618-A | ANTITUMOR AGENTS, TREATMENT OF SKIN DISORDERS | SRI INTERNATIONAL (US) | 1984-06-26 | — | — | US | disclosed |