Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4186791 | 0.93 | CYP3A4 (0.59) | CYP3A4ALDH1A1CYP1A2CA2AKR1C3 | |
| SCHEMBL11320167 | 0.89 | CYP3A4 (0.56) | CYP3A4ALDH1A1CYP1A2CA2AKR1C3 | |
| SCHEMBL10996267 | 0.86 | CYP3A4 (0.53) | CYP3A4ALDH1A1CYP1A2CA2AKR1C3 | |
| SCHEMBL487508 | 0.86 | ALDH1A1 (0.61) | CYP3A4ALDH1A1CYP1A2CYP2A6CA2 | |
| SCHEMBL16154053 | 0.84 | ALDH1A1 (0.63) | CYP3A4ALDH1A1KDM4ESLC6A2RAB9A | |
| SCHEMBL10017478 | 0.83 | ALDH1A1 (0.67) | CYP3A4ALDH1A1CA2LMNAMAPT | |
| SCHEMBL10989390 | 0.82 | PTPN11 (0.49) | CYP3A4ALDH1A1CA2KDM4ENPC1 | |
| SCHEMBL6338247 | 0.81 | CYP3A4 (0.49) | CYP3A4ALDH1A1CYP1A2CA2AKR1C3 | |
| SCHEMBL9762060 | 0.81 | GRIN2D (0.52) | CYP3A4ALDH1A1CA2KDM4ENPC1 | |
| SCHEMBL10017469 | 0.79 | ALDH1A1 (0.55) | CYP3A4ALDH1A1CA2LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221289-A1 | Compounds Comprising 2,6-Naphthyl Groups | BASF AKTIENGESELLSCHAFT (DE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221289-A1 | Compounds Comprising 2,6-Naphthyl Groups | SCO2, MT-CO1, CBR1 | CYP3A4 447/4885ALDH1A1 1451/4885CYP1A2 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.