SCHEMBL487508

SCHEMBL487508

CC(=O)OCc1ccc2ccccc2c1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.61
CYP3A4 P08684 1/20 0.53
TACR1 P25103 1/20 0.51
CYP1A2 P05177 2/20 0.50
SLC1A3 P43003 1/20 0.50
SLC1A2 P43004 1/20 0.50
SLC1A1 P43005 1/20 0.50
CYP2A6 P11509 1/20 0.50
CA2 P00918 1/20 0.50
GSTA2 P09210 1/20 0.48
GSTP1 P09211 1/20 0.48
GSTM1 P09488 1/20 0.48
RAB9A P51151 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
ALOX5 P09917 1/20 0.45
MAOB P27338 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4186791 0.93 CYP3A4 (0.59) ALDH1A1CYP3A4TACR1CYP1A2SLC1A3
SCHEMBL11320167 0.89 CYP3A4 (0.56) ALDH1A1CYP3A4TACR1CYP1A2SLC1A3
SCHEMBL14070555 0.86 CYP3A4 (0.53) ALDH1A1CYP3A4TACR1CYP1A2CYP2A6
SCHEMBL10996267 0.86 CYP3A4 (0.53) ALDH1A1CYP3A4TACR1CYP1A2SLC1A3
SCHEMBL28936084 0.85 CYP1A2 (0.54) TACR1CYP1A2SLC1A3SLC1A2SLC1A1
SCHEMBL6443298 0.84 SLC1A3 (0.55) TACR1CYP1A2SLC1A3SLC1A2SLC1A1
SCHEMBL6443296 0.84 SLC1A3 (0.51) TACR1CYP1A2SLC1A3SLC1A2SLC1A1
SCHEMBL2619047 0.83 TACR1 (0.47) ALDH1A1TACR1CYP1A2SLC1A3SLC1A2
SCHEMBL29503697 0.83 TACR1 (0.47) ALDH1A1TACR1CYP1A2SLC1A3SLC1A2
SCHEMBL14011321 0.83 TACR1 (0.52) ALDH1A1TACR1CYP1A2SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5670698-A Synthesis of 1-acetoxy-2-methylnaphthalene BRISTOL-MYERS SQUIBB COMPANY (US) 1997-09-23 US claimed
CN-118344271-A Alkoxy substituted benzoyl oxo cyclohexene sulfide compound, preparation method and application thereof 沈阳万菱生物技术有限公司 2024-07-16 CN disclosed
CN-118344301-A Tetra-substituted cyclohexene thioether compound, preparation method and application thereof 沈阳万菱生物技术有限公司 2024-07-16 CN disclosed
CN-118290317-A Trisubstituted cyclohexene sulfide compound and application thereof 沈阳万菱生物技术有限公司 2024-07-05 CN disclosed
CN-115397242-B Compound combination with excellent herbicidal activity 拜耳公司 2024-06-14 CN disclosed
US-11110050-B2 Hair styling method and kit thereof WELLA OPERATIONS US, LLC (US) 2021-09-07 US disclosed
WO-2021078174-A1 CHIRAL SULFUR OXIDE-CONTAINING ARYL FORMAMIDE COMPOUND AND SALT THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND APPLICATION 青岛清原化合物有限公司 2021-04-29 WO disclosed
US-20210018833-A1 CURABLE COMPOSITION FOR IMPRINTING, RELEASE AGENT, CURED PRODUCT, PATTERN FORMING METHOD, AND LITHOGRAPHY METHOD FUJIFILM CORPORATION (JP) 2021-01-21 US disclosed
US-20130338363-A1 SILANE COMPOUND, PRODUCTION METHOD THEREOF, AND RESIN COMPOSITION CONTAINING SILANE COMPOUND NIPPON SHOKUBAI CO., LTD. (JP) 2013-12-19 US disclosed
US-8541532-B2 Silane compound, production method thereof, and resin composition containing silane compound NIPPON SHOKUBAI CO., LTD. (JP) 2013-09-24 US disclosed
EP-0920853-B1 Hair dye compositions P & G CLAIROL INC (US) 2004-01-21 EP disclosed
EP-0999203-B1 Novel developer in oxidative hair dyeing CLAIROL INC (US) 2003-02-26 EP disclosed
US-6228130-B1 1-(2,5-DIAMINOPHENYL)ETHYLENE GLYCOL; WATER SOLUBLE; P-PHENYLENEDIAMINE REPLACEMENT BRISTOL-MYERS SQUIBB COMPANY 2001-05-08 US disclosed
EP-0999203-A1 Novel developer in oxidative hair dyeing Bristol-Myers Squibb Company (US) 2000-05-10 EP disclosed
EP-0825172-B1 Synthesis of 1-acetoxy-2-methylnaphthalene BRISTOL MYERS SQUIBB CO (US) 2000-04-26 EP disclosed
EP-0920853-A1 Hair dye compositions Bristol-Myers Squibb Company (US) 1999-06-09 EP disclosed
EP-0825172-A1 Synthesis of 1-acetoxy-2-methylnaphthalene Bristol-Myers Squibb Company (US) 1998-02-25 EP disclosed
US-5670698-A Synthesis of 1-acetoxy-2-methylnaphthalene BRISTOL-MYERS SQUIBB COMPANY (US) 1997-09-23 US disclosed
EP-0711283-A1 TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS PFIZER INC. (US) 1996-05-15 EP disclosed
WO-1995003281-A1 TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS PFIZER INC. (US) 1995-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11110050-B2 Hair styling method and kit thereof KIT, PRKDC, POLR1C ALDH1A1 4220/4885CYP3A4 4655/4885TACR1 848/4885
US-20130338363-A1 SILANE COMPOUND, PRODUCTION METHOD THEREOF, AND RESIN COMPOSITION CONTAINING SILANE COMPOUND ZYX, NOX3, NOXO1 ALDH1A1 1943/4885CYP3A4 1777/4885TACR1 2905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.