Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 12/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 12/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761664 | 0.82 | BRD4 (0.47) | BRD4EGLN1CYP1A2 | |
| SCHEMBL9761830 | 0.75 | BRD4 (0.41) | BRD4GRIN1GRIN2BNAMPT | |
| SCHEMBL9762213 | 0.74 | BRD4 (0.44) | BRD4CYP2C9 | |
| SCHEMBL9762493 | 0.73 | BRD4 (0.40) | BRD4 | |
| SCHEMBL7613547 | 0.73 | ELANE (0.50) | BRD4 | |
| SCHEMBL9762399 | 0.72 | BRD4 (0.35) | BRD4GRIN1GRIN2BCTDSP1EGLN1 | |
| SCHEMBL9761743 | 0.71 | BRD4 (0.38) | BRD4NAMPT | |
| SCHEMBL9761111 | 0.70 | CYP2C9 (0.38) | BRD4CYP2C9 | |
| SCHEMBL7615597 | 0.70 | PTGS1 (0.45) | BRD4 | |
| SCHEMBL2352063 | 0.69 | BRD4 (0.42) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066665-A | Cognition activators; alzheimer*s disease | WARNER-LAMBERT CO. (US) | 1991-11-19 | — | — | US | disclosed |