Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.33 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.33 |
| ▸ | EIF4E | P06730 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761664 | 0.82 | BRD4 (0.47) | BRD4 | |
| SCHEMBL9762213 | 0.80 | BRD4 (0.44) | BRD4 | |
| SCHEMBL9762147 | 0.75 | BRD4 (0.43) | BRD4NAMPTGRIN1GRIN2B | |
| SCHEMBL9760799 | 0.74 | BRD4 (0.37) | BRD4CYP1B1 | |
| SCHEMBL9761111 | 0.73 | CYP2C9 (0.38) | BRD4OPRM1 | |
| SCHEMBL9762460 | 0.72 | RIPK3 (0.37) | CYP1B1GRIN1GRIN2BRIPK3LOXL2 | |
| SCHEMBL9762493 | 0.70 | BRD4 (0.40) | BRD4LOXL2 | |
| SCHEMBL7613547 | 0.70 | ELANE (0.50) | BRD4 | |
| SCHEMBL9761584 | 0.70 | BRD4 (0.36) | BRD4PDE10A | |
| SCHEMBL2352063 | 0.69 | BRD4 (0.42) | BRD4BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066665-A | Cognition activators; alzheimer*s disease | WARNER-LAMBERT CO. (US) | 1991-11-19 | — | — | US | disclosed |