Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PARG | Q86W56 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761111 | 0.75 | CYP2C9 (0.38) | BRD4 | |
| SCHEMBL9761664 | 0.75 | BRD4 (0.47) | BRD4 | |
| SCHEMBL9762147 | 0.71 | BRD4 (0.43) | BRD4NAMPT | |
| SCHEMBL9760995 | 0.71 | CHRM2 (0.36) | PARG | |
| SCHEMBL9762586 | 0.71 | PARG (0.37) | BRD4PARGNAMPT | |
| SCHEMBL9760799 | 0.70 | BRD4 (0.37) | BRD4 | |
| SCHEMBL9762213 | 0.70 | BRD4 (0.44) | BRD4 | |
| SCHEMBL7613547 | 0.69 | ELANE (0.50) | BRD4 | |
| SCHEMBL9761584 | 0.69 | BRD4 (0.36) | BRD4PARG | |
| SCHEMBL2352063 | 0.68 | BRD4 (0.42) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066665-A | Cognition activators; alzheimer*s disease | WARNER-LAMBERT CO. (US) | 1991-11-19 | — | — | US | disclosed |