Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043787 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4EL3MBTL1HTTMAPT | |
| SCHEMBL9045620 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KDM4EL3MBTL1HTTMAPT | |
| SCHEMBL80329 | 0.73 | ALDH1A1 (1.00) | ALDH1A1ALOX15KDM4EL3MBTL1HTT | |
| SCHEMBL3916108 | 0.73 | ALDH1A1 (1.00) | ALDH1A1ALOX15KDM4EL3MBTL1HTT | |
| SCHEMBL9694344 | 0.72 | ALDH1A1 (0.44) | ALDH1A1KDM4EL3MBTL1HTTMAPT | |
| SCHEMBL9044331 | 0.72 | ALDH1A1 (0.44) | ALDH1A1KDM4EL3MBTL1HTTMAPT | |
| SCHEMBL1111522 | 0.71 | POLB (0.47) | ALDH1A1KDM4EL3MBTL1HTTMAPT | |
| SCHEMBL9763213 | 0.71 | ALDH1A1 (0.44) | ALDH1A1KDM4EL3MBTL1HTTMAPT | |
| SCHEMBL11271014 | 0.71 | ALDH1A1 (0.94) | ALDH1A1ALOX15KDM4EL3MBTL1HTT | |
| Hydrochloric Acid SCHEMBL10866136 | 0.71 | ALDH1A1 (0.94) | ALDH1A1ALOX15KDM4EL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270111-B1 | PYRIMIDINE DERIVATIVES AND AGRICULTURAL OR HORTICULTURAL FUNGICIDAL COMPOSITION CONTANING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4992438-A | Pyrimidine derivatives, process for preparing the same and agricultural or horticultural fungicidal composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| EP-0270111-A1 | Pyrimidine derivatives and agricultural or horticultural fungicidal composition contaning the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-06-08 | — | — | EP | disclosed |