Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511419 | 0.83 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL9043112 | 0.82 | ADORA2A (0.37) | ALDH1A1L3MBTL1MAPTHTTMEN1 | |
| SCHEMBL9043196 | 0.81 | FFAR1 (0.39) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL9694344 | 0.76 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPTHTTMEN1 | |
| SCHEMBL9043709 | 0.74 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPTHTTMEN1 | |
| SCHEMBL9641892 | 0.73 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPTHTTMEN1 | |
| SCHEMBL9042986 | 0.73 | HTT (0.44) | ALDH1A1L3MBTL1MAPTHTTMEN1 | |
| SCHEMBL20194845 | 0.73 | NCF1 (0.39) | ALDH1A1L3MBTL1MAPTHTTMEN1 | |
| SCHEMBL9763213 | 0.72 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPTHTTMEN1 | |
| SCHEMBL9762433 | 0.72 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1MAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358609-B1 | Parasiticide compounds | CIBA GEIGY AG (CH) | 1996-07-24 | — | — | EP | claimed |
| EP-0358609-A2 | Parasiticide compounds | CIBA-GEIGY AG (CH) | 1990-03-14 | — | — | EP | claimed |
| EP-0358609-B1 | Parasiticide compounds | CIBA GEIGY AG (CH) | 1996-07-24 | — | — | EP | disclosed |
| US-5175293-A | Substituted 2-aminopyrimidine derivatives | CIBA-GEIGY CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0358609-A2 | Parasiticide compounds | CIBA-GEIGY AG (CH) | 1990-03-14 | — | — | EP | disclosed |