Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763207 | 0.89 | LMNA (0.45) | ALDH1A1L3MBTL1HTTMAPTUSP2 | |
| SCHEMBL10668838 | 0.82 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1HTTMAPTUSP2 | |
| SCHEMBL9763444 | 0.73 | SMN1; SMN2 (0.39) | ALDH1A1MAPTKDM4ETSHRMEN1 | |
| SCHEMBL5516786 | 0.73 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1HTTMAPTKDM4E | |
| SCHEMBL43388 | 0.73 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1HTTMAPTKDM4E | |
| SCHEMBL1487730 | 0.72 | TSPO (0.41) | ALDH1A1HTTTSHRMEN1KMT2A | |
| SCHEMBL9694344 | 0.72 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1HTTMAPTUSP2 | |
| SCHEMBL9044331 | 0.72 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1HTTMAPTUSP2 | |
| SCHEMBL9762433 | 0.71 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1HTTMAPTUSP2 | |
| SCHEMBL1111522 | 0.71 | POLB (0.47) | ALDH1A1L3MBTL1HTTMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270111-B1 | PYRIMIDINE DERIVATIVES AND AGRICULTURAL OR HORTICULTURAL FUNGICIDAL COMPOSITION CONTANING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4992438-A | Pyrimidine derivatives, process for preparing the same and agricultural or horticultural fungicidal composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| US-4783459-A | Anilinopyrimidine fungicides | SCHERING AGROCHEMICALS LTD. (GB) | 1988-11-08 | — | — | US | disclosed |
| EP-0270111-A1 | Pyrimidine derivatives and agricultural or horticultural fungicidal composition contaning the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-06-08 | — | — | EP | disclosed |
| EP-0243136-A2 | Anilinopyrimidine fungicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1987-10-28 | — | — | EP | disclosed |