Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | EED | O75530 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MLNR | O43193 | 1/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HLA-A | P04439 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23696363 | 0.83 | KCNH2 (0.64) | HRH1TACR2TACR1EEDHTR1A | |
| SCHEMBL23696978 | 0.81 | SIGMAR1 (0.53) | HRH1TACR2TACR1EEDHTR1A | |
| SCHEMBL9762644 | 0.81 | KCNH2 (0.45) | HRH1SIGMAR1CYP2D6CHRM1KCNH2 | |
| SCHEMBL31582821 | 0.76 | HRH1 (0.53) | HRH1TACR2TACR1EEDHTR1A | |
| SCHEMBL31583414 | 0.73 | HTR1A (0.48) | HRH1TACR2TACR1EEDHTR1A | |
| SCHEMBL23696364 | 0.73 | MAOB (0.46) | KCNH2 | |
| SCHEMBL2157601 | 0.73 | KCNH2 (0.61) | HTR1ASLC6A4KCNH2 | |
| SCHEMBL9537962 | 0.72 | HTR1A (0.57) | HRH1TACR2TACR1EEDHTR1A | |
| SCHEMBL2157291 | 0.71 | SIGMAR1 (0.69) | SIGMAR1HRH3USP2ADRA1DADRA1A | |
| SCHEMBL5871773 | 0.71 | KCNH2 (0.62) | HRH1TACR2TACR1EEDHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667666-B2 | Methods and compositions for treatment of cancer | CFD RESEARCH CORPORATION (US) | 2023-06-06 | — | — | US | disclosed |
| US-11667666-B2 | Methods and compositions for treatment of cancer | CFD RESEARCH CORPORATION (US) | 2023-06-06 | — | — | US | disclosed |
| US-20210230212-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF CANCER | CFD RESEARCH CORPORATION | 2021-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667666-B2 | Methods and compositions for treatment of cancer | TEK, VHL, TIE1 | HRH1 4358/4885TACR2 3036/4885TACR1 2225/4885 |
| US-20210230212-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF CANCER | TEK, VHL, TIE1 | HRH1 4358/4885TACR2 3036/4885TACR1 2225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.