Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761257 | 0.78 | CCR6 (0.32) | MAPT | |
| SCHEMBL9760998 | 0.77 | MAPT (0.36) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL9761403 | 0.70 | ALDH1A1 (0.32) | MAPTALDH1A1 | |
| SCHEMBL9762608 | 0.69 | NPBWR1 (0.38) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL9760901 | 0.68 | MAPT (0.33) | MAPTPOLB | |
| SCHEMBL9762405 | 0.67 | MAPT (0.42) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL10400102 | 0.66 | MAPT (0.41) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL11710459 | 0.62 | MAPK8 (0.40) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL29242781 | 0.62 | MAPT (0.41) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL30677226 | 0.62 | MAPT (0.47) | MAPTLMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |