Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546205 | 0.88 | L3MBTL1 (0.41) | ALDH1A1KMT2ALMNANPSR1TSHR | |
| SCHEMBL24235642 | 0.86 | ALDH1A1 (0.37) | ALDH1A1KMT2ALMNANPSR1MAPT | |
| SCHEMBL26698331 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KMT2ANPSR1TSHRL3MBTL1 | |
| SCHEMBL16424346 | 0.85 | ALDH1A1 (0.39) | ALDH1A1KMT2ANPSR1MAPTTSHR | |
| SCHEMBL31094788 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KMT2ANPSR1TSHRL3MBTL1 | |
| SCHEMBL16423074 | 0.83 | ALDH1A1 (0.37) | ALDH1A1KMT2ALMNANPSR1MAPT | |
| SCHEMBL15615197 | 0.83 | THRB (0.35) | ALDH1A1KMT2AMEN1BCL2 | |
| SCHEMBL11704069 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KMT2ANPSR1TSHRL3MBTL1 | |
| SCHEMBL31724386 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KMT2ALMNANPSR1MAPT | |
| SCHEMBL25471357 | 0.81 | SLC6A2 (0.44) | ALDH1A1KMT2AMAPTTSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034381-A | Antagonist | CIBA-GEIGY CORPORATION (US) | 1991-07-23 | — | — | US | disclosed |