Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SNCA | P37840 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503334 | 0.98 | LMNA (0.59) | LMNATDP1KMT2AL3MBTL1SNCA | |
| Hydrochloric Acid SCHEMBL27365345 | 0.97 | LMNA (0.57) | LMNATDP1KMT2AL3MBTL1SNCA | |
| SCHEMBL21963615 | 0.88 | MAPT (0.63) | LMNAKMT2ASNCAALDH1A1KDM4E | |
| SCHEMBL21243068 | 0.85 | LMNA (0.62) | LMNATDP1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL1817895 | 0.80 | KMT2A (0.64) | LMNATDP1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL25009812 | 0.80 | L3MBTL1 (0.76) | LMNATDP1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL30556174 | 0.80 | L3MBTL1 (0.76) | LMNATDP1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL11524023 | 0.79 | L3MBTL1 (0.61) | LMNATDP1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL21946333 | 0.79 | KMT2A (0.51) | LMNATDP1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL14741028 | 0.78 | LMNA (0.66) | LMNATDP1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043162-A | Mixture of lower alkyl nicotinate and histamine hydrochloride | TRAGER SEYMOUR F (US) | 1991-08-27 | — | — | US | claimed |