Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503334 | 0.87 | LMNA (0.59) | LMNAKMT2ATDP1L3MBTL1ALDH1A1 | |
| Charcoal, Activated SCHEMBL9762824 | 0.85 | LMNA (0.57) | LMNAKMT2ATDP1L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27365345 | 0.85 | LMNA (0.57) | LMNAKMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL25009812 | 0.84 | L3MBTL1 (0.76) | LMNAKMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL30556174 | 0.84 | L3MBTL1 (0.76) | LMNAKMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL8922120 | 0.83 | L3MBTL1 (0.54) | LMNAKMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL8922122 | 0.83 | L3MBTL1 (0.54) | LMNAKMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL14741028 | 0.82 | LMNA (0.66) | LMNAKMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL17978281 | 0.82 | KMT2A (0.66) | LMNAKMT2ATDP1L3MBTL1ALDH1A1 | |
| Ethyl Nicotinate SCHEMBL8164637 | 0.81 | L3MBTL1 (0.71) | LMNAKMT2ATDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180521-B2 | Nicotinamide riboside analogs, pharmaceutical compositions, and uses thereof | METRO INTERNATIONAL BIOTECH, LLC (US) | 2021-11-23 | — | — | US | disclosed |
| US-20210032280-A1 | NICOTINAMIDE RIBOSIDE ANALOGS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | METRO INTERNATIONAL BIOTECH, LLC | 2021-02-04 | — | — | US | disclosed |
| WO-2019152416-A1 | NICOTINAMIDE RIBOSIDE ANALOGS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | METRO INTERNATIONAL BIOTECH, LLC (US) | 2019-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210032280-A1 | NICOTINAMIDE RIBOSIDE ANALOGS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | NAMPT, NADK, NNT | LMNA 1520/4885KMT2A 3784/4885TDP1 669/4885 |
| US-11180521-B2 | Nicotinamide riboside analogs, pharmaceutical compositions, and uses thereof | NAMPT, NADK, NNT | LMNA 1520/4885KMT2A 3784/4885TDP1 669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.