Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795119 | 0.81 | MCL1 (0.46) | ALDH1A1NPSR1MAPTMEN1KMT2A | |
| Sulfuric Acid SCHEMBL20984891 | 0.77 | TDP1 (0.51) | TDP1HDAC1HDAC8HDAC6HCRTR1 | |
| SCHEMBL10797278 | 0.74 | KCNQ2 (0.42) | SMN1; SMN2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9762907 | 0.73 | KMT2A (0.52) | HDAC8ALDH1A1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL9762866 | 0.72 | TDP1 (0.64) | TDP1HDAC1HDAC8HDAC6HCRTR1 | |
| Phosphoric Acid SCHEMBL28373873 | 0.71 | TDP1 (0.51) | TDP1HDAC1HDAC8HDAC6P2RX7 | |
| SCHEMBL7576195 | 0.70 | TDP1 (0.51) | TDP1HDAC1HDAC8HDAC6P2RX7 | |
| SCHEMBL9836766 | 0.70 | P2RX7 (0.58) | TDP1HDAC1HDAC8HDAC6HCRTR1 | |
| SCHEMBL30117898 | 0.70 | ALDH1A1 (0.64) | TDP1HDAC1HDAC8HDAC6HCRTR1 | |
| SCHEMBL2847925 | 0.70 | ALDH1A1 (0.64) | TDP1HDAC1HDAC8HDAC6HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003052-A | Monoazo fiber reactive dye for cellulose, polyamides, wool, silk, polyurethanes and leather | CIBA-GEIGY CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-4652634-A | Water-soluble monoazo compounds containing a N-(sulfoalkyl)-aniline coupling component and a fiber-reactive group of the vinylsulfonyl series in the phenyl or benzothiazole diazo component, suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |
| EP-0051808-B1 | WATER-SOLUBLE MONOAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-04 | — | — | EP | disclosed |
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |