Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11318950 | 0.85 | HPGD (0.45) | ALDH1A1MCOLN3HCRTR1HCRTR2L3MBTL1 | |
| SCHEMBL10797316 | 0.81 | HTT (0.54) | HTTALDH1A1PKMMCOLN3MAPT | |
| SCHEMBL11676571 | 0.74 | TSHR (0.43) | HTTALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL9762898 | 0.74 | HTT (0.46) | HTTALDH1A1PKMMCOLN3MAPT | |
| SCHEMBL10797166 | 0.73 | TAAR1 (0.45) | HTTALDH1A1MAPTHCRTR2L3MBTL1 | |
| SCHEMBL11690507 | 0.72 | CCR5 (0.50) | HTTALDH1A1PKMMCOLN3MAPT | |
| SCHEMBL11670505 | 0.72 | TSHR (0.45) | HTTALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL12046938 | 0.68 | ACHE (0.46) | ALDH1A1MCOLN3MAPTHCRTR1HCRTR2 | |
| SCHEMBL10797322 | 0.68 | HTT (0.45) | HTTPKMMCOLN3MAPTL3MBTL1 | |
| SCHEMBL9762907 | 0.67 | KMT2A (0.52) | ALDH1A1MAPTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003052-A | Monoazo fiber reactive dye for cellulose, polyamides, wool, silk, polyurethanes and leather | CIBA-GEIGY CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-4652634-A | Water-soluble monoazo compounds containing a N-(sulfoalkyl)-aniline coupling component and a fiber-reactive group of the vinylsulfonyl series in the phenyl or benzothiazole diazo component, suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |