Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357120 | 0.81 | MAPT (0.57) | MAPTHDAC6ALDH1A1TAAR1HTR3E | |
| SCHEMBL31601922 | 0.80 | CRHR1 (0.41) | MAPTCRHR1ALDH1A1HPGDEGFR | |
| SCHEMBL9762449 | 0.80 | CRHR1 (0.41) | MAPTCRHR1ALDH1A1HPGDEGFR | |
| SCHEMBL11408687 | 0.79 | MAPT (0.54) | MAPTALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL14189370 | 0.79 | TAAR1 (0.72) | TAAR1 | |
| SCHEMBL632302 | 0.79 | HDAC6 (0.47) | MAPTHDAC6CRHR1ALDH1A1TAAR1 | |
| SCHEMBL6572500 | 0.79 | MAPT (0.40) | MAPTHDAC6CRHR1TAAR1MEN1 | |
| SCHEMBL30817924 | 0.79 | MTNR1A (0.52) | AOC3 | |
| SCHEMBL21614161 | 0.79 | MTNR1A (0.52) | AOC3 | |
| SCHEMBL10350091 | 0.79 | CYP3A4 (0.41) | MAPTHDAC6CRHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997918-A | Benzthiazolium azo dyes | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0105031-A2 | Cationic azo dyestuffs | CIBA-GEIGY AG (CH) | 1984-04-04 | — | — | EP | disclosed |