Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.36 |
| ▸ | ABAT | P80404 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2587522 | 0.85 | THRB (0.64) | THRBKMT2AHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL4132764 | 0.83 | THRB (0.55) | THRBKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL25041907 | 0.83 | THRB (0.55) | THRBKMT2AHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL7455238 | 0.82 | HSD17B10 (0.53) | THRBKMT2AHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL21914775 | 0.82 | THRB (0.53) | THRBKMT2AHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL1894950 | 0.82 | HSD17B10 (0.53) | THRBKMT2AHSD17B10ALDH1A1PKM | |
| SCHEMBL18619583 | 0.82 | ALDH5A1 (0.57) | THRBKMT2AHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8836170 | 0.80 | THRB (0.51) | THRBKMT2AHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL3797234 | 0.80 | THRB (0.51) | THRBKMT2AHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL898885 | 0.80 | MAPT (0.57) | THRBKMT2ASMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075456-A | Monomers for acrylic esters; photoresists, prepregs | CIBA-GEIGY CORPORATION (US) | 1991-12-24 | — | — | US | disclosed |