Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.32 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764001 | 0.95 | DDB1 (0.32) | DDB1CRBNHSD17B10TPSAB1TPSD1 | |
| SCHEMBL6494880 | 0.83 | KLK7 (0.36) | DDB1CRBNHSD17B10TPSAB1TPSD1 | |
| SCHEMBL3394051 | 0.81 | DDB1 (0.34) | DDB1CRBNHSD17B10TPSAB1TPSD1 | |
| SCHEMBL7698258 | 0.79 | HSD17B10 (0.33) | DDB1CRBNHSD17B10TPSAB1TPSD1 | |
| SCHEMBL7698260 | 0.79 | HSD17B10 (0.33) | DDB1CRBNHSD17B10TPSAB1TPSD1 | |
| SCHEMBL7172090 | 0.79 | FAAH (0.35) | DDB1CRBNHSD17B10TPSAB1TPSD1 | |
| SCHEMBL10435137 | 0.77 | MME (0.37) | DDB1CRBNHSD17B10TPSAB1TPSD1 | |
| SCHEMBL31486428 | 0.77 | KLK7 (0.49) | NR1H2STSKLK7 | |
| SCHEMBL8669568 | 0.77 | KLK7 (0.49) | NR1H2STSKLK7 | |
| SCHEMBL5065670 | 0.77 | KLK7 (0.49) | NR1H2STSKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021439-A | Senile dementia and memory dysfunction | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0367393-A2 | New heterocyclic compounds, production and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1990-05-09 | — | — | EP | disclosed |