Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698260 | 1.00 | HSD17B10 (0.33) | HSD17B10TPSAB1TPSD1TPSG1NR1H2 | |
| SCHEMBL5957974 | 0.85 | MEN1 (0.34) | HSD17B10NR1H2MEN1ALDH1A1MAPT | |
| SCHEMBL6494880 | 0.84 | KLK7 (0.36) | HSD17B10TPSAB1TPSD1TPSG1NR1H2 | |
| SCHEMBL3394051 | 0.82 | DDB1 (0.34) | HSD17B10TPSAB1TPSD1TPSG1NR1H2 | |
| SCHEMBL7703658 | 0.81 | AGTR2 (0.38) | STSKLK7KDM4E | |
| SCHEMBL7703661 | 0.81 | AGTR2 (0.38) | STSKLK7KDM4E | |
| SCHEMBL10435137 | 0.80 | MME (0.37) | HSD17B10TPSAB1TPSD1TPSG1NR1H2 | |
| SCHEMBL7172090 | 0.80 | FAAH (0.35) | HSD17B10TPSAB1TPSD1TPSG1NR1H2 | |
| SCHEMBL9763142 | 0.79 | DDB1 (0.33) | HSD17B10TPSAB1TPSD1TPSG1NR1H2 | |
| SCHEMBL8669568 | 0.78 | KLK7 (0.49) | NR1H2STSKLK7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002014261-A2 | 4-SUBSTITUTED D-GLUTAMIC ACID DERIVATIVES FOR USE AS ANTIBIOTIC | ELI LILLY AND COMPANY (US) | 2002-02-21 | — | — | WO | disclosed |