Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 5/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175859 | 0.88 | AGTR2 (0.53) | AGTR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9175852 | 0.88 | AGTR2 (0.53) | AGTR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6683695 | 0.88 | AGTR2 (0.55) | AGTR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL14569818 | 0.84 | AGTR2 (0.46) | AGTR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL14546519 | 0.84 | AGTR2 (0.46) | AGTR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10137620 | 0.84 | AGTR2 (0.46) | AGTR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8280446 | 0.84 | AGTR2 (0.46) | AGTR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6285084 | 0.84 | AGTR2 (0.52) | AGTR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6343357 | 0.84 | AGTR2 (0.52) | AGTR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL16256994 | 0.83 | AGTR2 (0.51) | AGTR2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013842-A | Synthesis of chiral pyrrolidine and piperidine glycosidase inhibitors | MONSANTO COMPANY (US) | 1991-05-07 | — | — | US | disclosed |