Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTPRF | P10586 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11750936 | 0.84 | SMN1; SMN2 (0.47) | ALDH1A1MAPTMEN1KMT2APTPN2 | |
| SCHEMBL456296 | 0.80 | FOLH1 (0.43) | KDM4EALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL10076826 | 0.76 | MAOB (0.43) | MEN1KMT2A | |
| SCHEMBL9574173 | 0.76 | MAOB (0.43) | MEN1KMT2A | |
| SCHEMBL10488546 | 0.75 | RAF1 (0.38) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10464519 | 0.75 | KDM4E (0.39) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL1316513 | 0.73 | LRRK2 (0.63) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL1191417 | 0.72 | KDM4E (0.46) | KDM4EALDH1A1GAA | |
| SCHEMBL9763759 | 0.71 | ADRB2 (0.41) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL10477760 | 0.71 | MEN1 (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |