Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10076826 | 0.98 | MAOB (0.43) | MAOBAPPMEN1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL11671567 | 0.90 | APP (0.47) | MAOBAPPMEN1LMNAKMT2A | |
| SCHEMBL10592068 | 0.83 | MAOB (0.40) | MAOBAPPMEN1KMT2ABCHE | |
| SCHEMBL10477860 | 0.81 | KDM4E (0.41) | MAOBMEN1LMNAKMT2ABCHE | |
| SCHEMBL9668333 | 0.81 | MAOB (0.42) | MAOBAPPMEN1KMT2ABCHE | |
| SCHEMBL10077369 | 0.81 | CDK1 (0.42) | MAOBMEN1KMT2ABCHEACHE | |
| SCHEMBL456296 | 0.78 | FOLH1 (0.43) | MAOBEGFR | |
| SCHEMBL11750936 | 0.78 | SMN1; SMN2 (0.47) | MAOBMEN1LMNAKMT2AEGFR | |
| SCHEMBL9763320 | 0.76 | KDM4E (0.40) | MEN1KMT2A | |
| SCHEMBL10488546 | 0.75 | RAF1 (0.38) | MAOBMEN1KMT2ABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243076-A | Adrenergic stimulant intermediates | GLAXO GROUP LTD. | 1993-09-07 | — | — | US | disclosed |
| US-5225445-A | Respiratory system disorders | GLAXO GROUP LTD. | 1993-07-06 | — | — | US | disclosed |
| US-5126375-A | Asthma, chronic bronchitis | GLAXO GROUP LTD. (GB) | 1992-06-30 | — | — | US | disclosed |
| US-5091422-A | Treating inflammatory or allergic skin disease, lowering gastric acidity | GLAXO GROUP LIMITED (GB) | 1992-02-25 | — | — | US | disclosed |
| US-4992474-A | Adrenergic stimulants | GLAXO GROUP LTD. (GB) | 1991-02-12 | — | — | US | disclosed |