SCHEMBL9763376

SCHEMBL9763376

C=CCN(CC=C)c1cccnc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 2/20 0.39
CYP1A2 P05177 2/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2A6 P11509 1/20 0.37
CHRNB2 P17787 1/20 0.36
CHRNA4 P43681 1/20 0.36
CHKA P35790 1/20 0.36
MAPT P10636 2/20 0.36
POLB P06746 1/20 0.36
MAPK1 P28482 1/20 0.36
KCNN4 O15554 1/20 0.36
PKM P14618 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SLC6A2 P23975 1/20 0.35
CYP2D6 P10635 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12072374 0.90 CHRNB2 (0.41) KCNA5ALDH1A1CYP3A4CHRNB2CHRNA4
SCHEMBL28451780 0.85 TSHR (0.49) KCNA5CYP1A2ALDH1A1CHRNB2CHRNA4
SCHEMBL28341883 0.83 CHRNA7 (0.43) KCNA5CYP1A2CYP3A4MAPTPOLB
SCHEMBL28440491 0.81 KCNA5 (0.44) KCNA5MAPTPOLBMAPK1KCNN4
SCHEMBL14415500 0.81 CHRNB2 (0.42) KCNA5CYP2A6CHRNB2CHRNA4KCNN4
SCHEMBL12057237 0.78 CHRNB2 (0.35) KCNA5CYP3A4CHRNB2CHRNA4MAPT
SCHEMBL28444925 0.76 RAB9A (0.42) ALDH1A1CYP3A4CYP2A6CHRNB2CHRNA4
SCHEMBL28897155 0.76 CYP19A1 (0.39) ALDH1A1CYP3A4MAPTSMN1; SMN2
SCHEMBL418658 0.75 CHKA (0.46) CYP1A2ALDH1A1CHKAMAPTSMN1; SMN2
SCHEMBL11032897 0.74 CHKA (0.46) CYP1A2ALDH1A1CHKAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037469-A Herbicides MONSANTO COMPANY (US) 1991-08-06 US disclosed