Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TXN | P10599 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mepanipyrim SCHEMBL29672635 | 0.85 | TAAR1 (0.55) | KCNH3NPC1RAB9ASMN1; SMN2MEN1 | |
| Mepanipyrim SCHEMBL22040 | 0.85 | TAAR1 (0.55) | KCNH3NPC1RAB9ASMN1; SMN2MEN1 | |
| Mepanipyrim SCHEMBL28756483 | 0.84 | TAAR1 (0.54) | KCNH3NPC1RAB9ASMN1; SMN2MEN1 | |
| Mepanipyrim SCHEMBL28515840 | 0.79 | RAB9A (0.50) | NPC1RAB9AL3MBTL1SMN1; SMN2MEN1 | |
| Mepanipyrim SCHEMBL26109940 | 0.79 | TAAR1 (0.49) | KCNH3NPC1RAB9ASMN1; SMN2KDM4E | |
| Mepanipyrim SCHEMBL9795913 | 0.78 | TAAR1 (0.48) | NPC1RAB9AL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL6964614 | 0.75 | TXN (0.54) | KCNH3NPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL6957616 | 0.75 | RAB9A (0.51) | KCNH3NPC1RAB9AL3MBTL1SMN1; SMN2 | |
| Mepanipyrim SCHEMBL18132072 | 0.74 | TAAR1 (0.44) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| Mepanipyrim SCHEMBL5182844 | 0.73 | SMN1; SMN2 (0.43) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270111-B1 | PYRIMIDINE DERIVATIVES AND AGRICULTURAL OR HORTICULTURAL FUNGICIDAL COMPOSITION CONTANING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4992438-A | Pyrimidine derivatives, process for preparing the same and agricultural or horticultural fungicidal composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| EP-0270111-A1 | Pyrimidine derivatives and agricultural or horticultural fungicidal composition contaning the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-06-08 | — | — | EP | disclosed |