Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763372 | 0.88 | CHRM2 (0.64) | CHRM2KDM4EMEN1KMT2AMAOA | |
| SCHEMBL10477830 | 0.83 | CHRM2 (0.64) | CHRM2KDM4EMEN1KMT2AMAOA | |
| SCHEMBL2572147 | 0.82 | CHRM2 (0.46) | CHRM2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL10477755 | 0.81 | SIGMAR1 (0.69) | CHRM2MEN1KMT2AMAOASIGMAR1 | |
| SCHEMBL9764394 | 0.81 | SIGMAR1 (0.69) | CHRM2MEN1KMT2AMAOASIGMAR1 | |
| SCHEMBL9763338 | 0.80 | TSHR (0.48) | MEN1KMT2AMAOASIGMAR1MAPT | |
| SCHEMBL15264813 | 0.80 | ALDH1A1 (0.61) | MEN1KMT2AMAOASIGMAR1MAPT | |
| SCHEMBL18994884 | 0.80 | ALDH1A1 (0.53) | CHRM2KDM4EMEN1KMT2AMAOA | |
| Hydrochloric Acid SCHEMBL9258435 | 0.79 | SIGMAR1 (0.67) | CHRM2MEN1KMT2AMAOASIGMAR1 | |
| SCHEMBL9810822 | 0.78 | TSHR (0.57) | MEN1KMT2AMAOASIGMAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |